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| Product Name | Recombinant Mouse RNA polymerase II subunit A C-terminal domain phosphatase (Ctdp1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 24kDa. Partial: 178-341aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | TFIIF-associating CTD phosphatase |
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| Gene, Accession, CAS # | Ctdp1, UniProt: Q7TSG2 |
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| Catalog # | RPC23208 |
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| Order / More Info | Recombinant Mouse RNA polymerase II subunit A C-terminal domain phosphatase (Ctdp1), partial from BIOMATIK |
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| Product Specific References | n/a |
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