| 产品详情 |
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| Antigenic Specificity | COL17A1 |
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| Clone | 2C3 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1000-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | COL17A1 Monoclonal Antibody (2C3). COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa. |
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| Immunogen | n/a |
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| Other Names | COL17A1; BP180, BPAG2; Collagen alpha-1(XVII) chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2 |
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| Gene, Accession # | Entrez: 12821, 1308, 294027; Uniprot: Q07563, Q9UMD9 |
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| Catalog # | MA5-24848 |
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| Price | |
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| Order / More Info | COL17A1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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