| 产品详情 |
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| Antigenic Specificity | GP130 |
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| Clone | KGP130 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.125 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GP130 Monoclonal Antibody (KGP130), PE, eBioscience™. The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript v |
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| Immunogen | n/a |
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| Other Names | CD130; CD130 antigen; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6 receptor subunit beta; IL-6R subunit beta; IL6R-beta; IL6ST; interleukin receptor beta chain; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha |
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| Gene, Accession # | Entrez: 16195; Uniprot: Q00560 |
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| Catalog # | 12-1302-80 |
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| Price | |
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| Order / More Info | GP130 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28615031, 29507229 |
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