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Antigenic Specificity | Adhesion Molecule with Ig-Like Domain 1 (AMIGO1) (aa 554-574), (C-Term), (Cytoplasmic) |
Clone | S86-36 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | phycoerythrin (PE) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction. Cellular Localization: Cell Membrane, Cell projection | Axon |
Immunogen | Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1 |
Other Names | A|Amigo|ali2|AMIGO|AMIGO-1 |
Gene, Accession # | Gene ID: 57463,229715,295365 |
Catalog # | ABIN2483816 |
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Order / More Info | Adhesion Molecule with Ig-Like Domain 1 (AMIGO1) (aa 554-574), (C-Term), (Cytoplasmic) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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