产品详情 |
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Antigenic Specificity | CD28 |
Clone | CD28.6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | unconjugated, functional grade |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD28 Monoclonal Antibody (CD28.6), Functional Grade, eBioscience™. CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ |
Immunogen | n/a |
Other Names | MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28 |
Gene, Accession # | Entrez: 940; Uniprot: P10747 |
Catalog # | 16-0288-85 |
Price | |
Order / More Info | CD28 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15987711, 20053772, 20068105, 20667896, 21283755, 21953144, 23024058, 23864893, 23958647, 24469820, 25092887, 25339666, 25532725, 25833964, 26185130, 26469402 |
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