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| Antigenic Specificity | CD28 |
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| Clone | JJ319 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 500 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1.0 µg/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD28 Monoclonal Antibody (JJ319), FITC. CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thym |
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| Immunogen | n/a |
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| Other Names | MGC138290, Tp44, CD28 antigen, T-cell-specific surface glycoprotein CD28 |
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| Gene, Accession # | Entrez: 25660; Uniprot: P31042 |
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| Catalog # | MA5-17472 |
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| Price | |
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| Order / More Info | CD28 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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