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| Antigenic Specificity | MSH2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | Alexa Fluor® 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MSH2 Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides |
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| Immunogen | KLH conjugated synthetic peptide derived from human MSH-2. Immunogen Range: 80-130/935 |
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| Other Names | FCC1; COCA1; HNPCC; LCFS2; HNPCC1; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2; MSH2 |
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| Gene, Accession # | Gene ID: 4436, SwissProt: P43246 |
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| Catalog # | bs-0758R-A488 |
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| Price | |
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| Order / More Info | MSH2 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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