| 产品详情 |
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| Antigenic Specificity | MSH6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MSH6 Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstrea |
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| Immunogen | KLH conjugated synthetic peptide derived from human MSH6. Immunogen Range: 830-880/1360 |
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| Other Names | GTBP; HSAP; p160; GTMBP; HNPCC5; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; MutS-alpha 160 kDa subunit; MSH6 |
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| Gene, Accession # | Gene ID: 2956, SwissProt: P52701 |
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| Catalog # | bs-3804R-A647 |
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| Price | |
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| Order / More Info | MSH6 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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