| 产品详情 |
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| Antigenic Specificity | ASCL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ASCL1 Polyclonal Antibody. ASCL1 (ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system. Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons. ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system. The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features. Mapping to human chromosome 12, the ASCL1 |
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| Immunogen | n/a |
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| Other Names | bHLHa46, MASH1, HASH1, achaete-scute complex homolog 1 (Drosophila), ASH1 |
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| Gene, Accession # | Entrez: 429, 64186; Uniprot: P19359, P50553 |
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| Catalog # | PA5-77868 |
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| Price | |
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| Order / More Info | ASCL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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