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| Product Name | STO-609 (acetate) |
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| Description | Purity >98%. STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKAlpha and CaMKKBeta (Ki = 80 and 15 ng/ml, respectively). It also blocks autophosphorylation of both isoforms. STO-609 less potently inhibits CaMKII (IC50 = 10 µg/ml) and is minimally effective against several related kinases. It is bound, in CaMKKBeta, in the ATP-binding pocket found in the kinase domain. STO-609 is used to evaluate the action of CaMKK isoforms both in vitro and in cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, monoacetate |
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| Gene, Accession, CAS # | CAS: 1173022-21-3 |
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| Catalog # | LS-H10050 |
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| Order / More Info | STO-609 (acetate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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