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| Product Name | Dectin 2a, Recombinant, Mouse (CLEC6A, CLECSF10, NKCL) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE and visualized by silver stain. Dectin-2α, also known as CLEC6A, CLECSF10, and NKCL, belongs to the C-type lectin family of transmembrane immune regulatory glycoproteins. Dectin-2α, CLEC4A/DCIR, CLEC4B/DCAR, CLEC4C/DLEC, CLEC4D/MCL, and CLEC4E/mincle constitute a subgroup of these molecules that exhibit approximately 40% aa sequence identity in their extracellular domains (ECD) and have a conserved cysteine spacing in their carbohydrate recognition domains (CRD). 1,2 Mature mouse dectin-2α consists of a short cytoplasmic tail, a transmembrane segment, and an ECD with a stalk region and one CRD. 3,4 Alternate splicing leads to partial deletion of the transmembrane segment and stalk (β isoform) or a portion of the CRD (γ isoform). 4 The full length dectin-2α isoform is a 27 kD molecule that is primarily expressed on the surface of tissue macrophages and their precursors. 3-6 The CRD of dectin-2α contains an |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9JKF4 |
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| Catalog # | D1876-51 |
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| Order / More Info | Dectin 2a, Recombinant, Mouse (CLEC6A, CLECSF10, NKCL) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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