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Antigenic Specificity | IKK beta Ser476 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Alexa Fluor® 750 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IKK beta (Ser476) Polyclonal Antibody, Alexa Fluor® 750 Conjugated. • Target Background: IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphoryl |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Ser476 |
Other Names | Phosphorylated, phospho-IKK beta phospho S476; IKK beta phospho Ser476; p-IKK beta Ser476; IKKI kappa B kinase 2; IKKβ; IKK β; I kappa B kinase beta; IkBKB; IKK 2; IKK B; IKK beta; IKK2; IKKB; Inhibitor of kappa light chain gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta; Inhibitor of nuclear factor kappa B kinase beta subunit; Inhibitor of nuclear factor kappa B kinase subunit beta; MGC131801; NFKBIKB; Nuclear factor NF kappa B inhibitor kinase beta; Nuclear factor of kappa light chain gene enhancer in B cells inhibitor; IKKB_HUMAN. |
Gene, Accession # | Gene ID: 3551 |
Catalog # | bs-5442R-A750 |
Price | |
Order / More Info | IKK beta Ser476 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |