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Antigenic Specificity | IKK beta Tyr199 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 647 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IKK beta (Tyr199) Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Tyr199. Immunogen Range: 180-230/756 |
Other Names | Phosphorylated, phospho-IKK2; IKKB; IMD15; NFKBIKB; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IkBKB; I-kappa-B kinase 2; Nuclear factor NF-kappa-B inhibitor kinase beta |
Gene, Accession # | Gene ID: 3551, SwissProt: O14920 |
Catalog # | bs-3232R-A647 |
Price | |
Order / More Info | IKK beta Tyr199 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |