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| Product Name | Bone Morphogenetic Protein 10, Recombinant, Human (BMP10) |
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| Description | Purity ~97%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: ≤1EU/ug (LAL). The mature recombinant human BMP-10, generated by the proteolytic removal of the signal peptide and the propeptide, is a disulfide-linked homodimeric protein. Based on N-terminal sequencing, the mature recombinant human BMP-10 starts at Asn 317. The monomer has a calculated molecular mass of 12.2kD and migrates as an approximately 12.2kD protein in SDS-PAGE under reducing conditions. Source: Recombinant corresponding to Asn317-Arg424 from human BMP10 expressed in CHO cells (O95393). Activity: Measured by its ability to induce alkaline phosphatase synthesis by MC3T3E1 osteoblastic cells (Mazerbourg, S. et al., 2005, J. Biol. Chem. 280:32122). The ED50 for this effect is typically 15-60ng/mL. Reconstitution: It is recommended that sterile 4mM HCI containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10ug/mL. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 27302, SwissProt: O95393 |
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| Catalog # | B2553-37A |
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| Order / More Info | Bone Morphogenetic Protein 10, Recombinant, Human (BMP10) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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