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Antigenic Specificity | Glutamate Receptor, Metabotropic 2 (GRM2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The receptors in group II, including mGluRs 2 and 3, and group III, including mGluRs 4, 6, 7, and 8, (with some exceptions) prevent the formation of cyclic adenosine monophosphate, or cAMP, by activating a G protein that inhibits the enzyme adenylyl cyclase, which forms cAMP from ATP. |
Immunogen | GRM2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen. |
Other Names | GLUR2|GPRC1B|MGLUR2|mGlu2|4930441L02Rik|Gprc1b|mGluR2|mGluR7 |
Gene, Accession # | Gene ID: 2912 |
Catalog # | ABIN636930 |
Price | |
Order / More Info | Glutamate Receptor, Metabotropic 2 (GRM2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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