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Antigenic Specificity | Calreticulin |
Clone | 1G6A7 |
Host Species | Mouse |
Reactive Species | human, mouse, nonhuman primate |
Isotype | IgG2a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1-3 µg/mL, Immunocytochemistry: 1:200 - 1:1000, Immunofluorescence: 1:200 - 1:1000, Immunohistochemistry: 1:200 - 1:1000, Western Blot: 1:500 - 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calreticulin Monoclonal Antibody (1G6A7). Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis. |
Immunogen | n/a |
Other Names | RO; CRT; SSA; cC1qR; FLJ26680; CALR |
Gene, Accession # | Entrez: 12317, 811; Uniprot: P14211, P27797 |
Catalog # | MA5-15382 |
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Order / More Info | Calreticulin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19805615, 25429433 |
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