| 产品详情 |
| Edit |   |
|---|
| Product Name | Acidic Mammalian Chitinase Inhibitor Screening Kit (Fluor) |
|---|
| Description | Acidic Mammalian Chitinase (AMCase) belongs to the glycosyl hydrolase-18 family (EC 3.2.1.14), which is capable of hydrolyzing the Beta-(1, 4)-linkage between the adjacent N-acetyl glucosamine residues of chitin. AMCase is relatively abundant in the gastrointestinal tract and lung. It is highly expressed in the lungs of asthmatic patients and asthma animal models. In addition, the change in AMCase expression can be used to monitor Th-2/IL-13 mediated immune response and inflammation. Inhibition of AMCase activity has been considered as a therapeutic strategy to alleviate symptoms of allergic airway inflammation. Thus, there is a need to identify AMCase inhibitors as potential candidates to treat and/or prevent asthma. The Acidic Mammalian Chitinase Inhibitor Screening Kit uses Bisdionin F- a highly selective AMCase inhibitor as positive control and it provides a simple, rapid, sensitive and reliable test suitable for screening/characterizing AMCase inhibitors. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | Screening/characterizing/studying Mammalian Chitinase inhibitors/activators |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | LS-K628 |
|---|
| Price | |
|---|
| Order / More Info | Acidic Mammalian Chitinase Inhibitor Screening Kit (Fluor) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|