| 产品详情 |
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| Product Name | NVP-TAE684 |
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| Description | Purity >98% by HPLC. A potent and selective ALK (anaplastic lymphoma kinase) inhibitor that blocked the growth of ALCL (anaplastic large cell lymphoma)-derived and ALK-dependent cell lines with IC50 = 2-10 nM. NVP-TAE684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK (Nucleophosmin-anaplastic lymphoma kinase) and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl-N2-(2-methoxy-4-(4-methylpiperazin-1-yl)-piperidin-1-yl)phenyl)pyrimidine-2,4-diamine |
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| Gene, Accession, CAS # | CAS: 761439-42-3 |
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| Catalog # | LS-H2390 |
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| Order / More Info | NVP-TAE684 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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