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Antigenic Specificity | KLHL12 |
Clone | OTI4E1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KLHL12 Monoclonal Antibody (OTI4E1). Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland. |
Immunogen | n/a |
Other Names | C3IP1; DKIR; CUL3-interacting protein 1; kelch-like protein 12; kelch-like protein C3IP1 |
Gene, Accession # | Entrez: 59349; Uniprot: Q53G59 |
Catalog # | MA5-26584 |
Price | |
Order / More Info | KLHL12 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |