| 产品详情 |
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| Product Name | CUR 61414 |
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| Description | Purity >98%. CUR 61414 is a potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM). It binds directly with the pathway activator Smoothened (Ki = 44 nM). CUR 61414 blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in mouse skin. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-butanamide, G-856 |
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| Gene, Accession, CAS # | CAS: 334998-36-6 |
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| Catalog # | LS-H7271 |
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| Order / More Info | CUR 61414 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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