产品详情 |
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Antigenic Specificity | TNIP1 |
Clone | 1A11E3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNIP1 Monoclonal Antibody (1A11E3). Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal. Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. |
Immunogen | n/a |
Other Names | ABIN-1, NAF1, VAN, nip40-1, HIV-1 Nef-interacting protein, Nef-associated factor 1 SNP, TNFAIP3-interacting protein 1, virion-associated nuclear shuttling protein |
Gene, Accession # | Entrez: 10318; Uniprot: Q15025 |
Catalog # | 37-6100 |
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Order / More Info | TNIP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19277210, 21885437, 23749299, 27113748 |
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