| 产品详情 |
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| Antigenic Specificity | TNIP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNIP2 Polyclonal Antibody. TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kappa-B-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pa |
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| Immunogen | n/a |
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| Other Names | ABIN2, FLIP1, KLIP, A20-binding inhibitor of NF-kappa-B activation 2, A20-binding inhibitor of NF-kappaB activation-2, TNFAIP3-interacting protein 2, fetal liver LKB1-interacting protein |
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| Gene, Accession # | Entrez: 79155; Uniprot: Q8NFZ5 |
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| Catalog # | PA5-62077 |
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| Price | |
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| Order / More Info | TNIP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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