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Product Name | Calyculin A |
Description | Purity >99%. Calyculin A is a natural, cell-permeable inhibitor of the serine-threonine protein phosphatases (PP) PP1 and PP2A (IC50 s = 0.3-0.7 and 0.5-1 nM, respectively). It is without significant effect against PP2B, PP2C, and PP4. Through its effects on PP1 and PP2A, calyculin A has been shown to either promote or inhibit cancer cell growth in tumor cell lines and animal models. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraen-1-yl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propen-1-yl]-2-o, (-)-Calyculin A |
Gene, Accession, CAS # | CAS: 101932-71-2 |
Catalog # | LS-H6972 |
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Order / More Info | Calyculin A from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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