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| Product Name | Human HCC-1 protein |
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| Description | Human CCL14 is belonging to the CC chemokine family. It is encoded by the gene CCL14. CCL14 has two isoforms, CCL14a (HCC-1) and CCL14b (HCC-3). The sequence of HCC-3 differs from HCC-1 as follow: 27-27 R-QTGGKPKVVKIQLKLVG. CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure. The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood. CCL14 promotes chemotaxis of T lymphocytes, monocytes and eosinophils, and inhibits infection of M tropic human immunodeficiency virus type 1 and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 (66 a.a.) contains 66 amino acid residues and activation of the HCC 1/CCL14a precursor to active peptide is mediated by the urokinase type plasminogen activator or plasmin. MW: 7.8 kDa. Purity > 95 % by SDS-PAGE and HPLC analyses |
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| Size | 2 ug, 10 ug, 1 mg, 100 ug, 250 ug, 500 ug |
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| Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in 2xPBS, pH 7.4, 5 % trehalose |
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| Applications | HPLC, SDS-PAGE |
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| Other Names | Human Hemofiltrate CC Chemokine-1, 66a.a./CCL14 protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | orb107735 |
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| Order / More Info | Human HCC-1 protein from BIORBYT LTD. |
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| Product Specific References | n/a |
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