| 产品详情 |
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| Product Name | Jacaric Acid |
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| Description | Purity >95%. Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ?-6 triene isomer of Gamma-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 µM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant Alpha-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conjugated linoleic acid , which is also cytotoxic to cancer cells. Jacaric acid inhibits cyclooxygenase-1 in vitro (Ki = 1.7 µM) and, with long term feeding, decreases stearoyl-CoA desaturase expression and activity in mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8Z,10E,12Z-octadecatrienoic acid, 8(Z),10(E),12(Z)-Octadecatrienoic Acid |
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| Gene, Accession, CAS # | CAS: 28872-28-8 |
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| Catalog # | LS-H8276 |
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| Price | |
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| Order / More Info | Jacaric Acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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