产品详情 |
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Antigenic Specificity | Cdc42EP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cdc42EP2 Polyclonal Antibody. CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. |
Immunogen | n/a |
Other Names | BORG1, CEP2, CRIB-containing BOGR1 protein, binder of Rho GTPases 1, cdc42 effector protein 2 |
Gene, Accession # | Entrez: 104252; Uniprot: Q8JZX9 |
Catalog # | PA5-31049 |
Price | |
Order / More Info | Cdc42EP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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