| Edit |   |
|---|
| Antigenic Specificity | Merlin (Ser518) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | Alexa Fluor® 350 conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IF(IHC-P) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Merlin (Ser518) Antibody, Alexa Fluor® 350 Conjugated. • Target Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppress |
|---|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Merlin around the phosphorylation site of Ser518. Immunogen Range: 500-545/590 |
|---|
| Other Names | Phosphorylated, phospho-ACN; SCH; BANF; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin; NF2 |
|---|
| Gene, Accession # | Gene ID: 4771, SwissProt: P35240 |
|---|
| Catalog # | bs-3291R-A350 |
|---|
| Price | |
|---|
| Order / More Info | Merlin (Ser518) Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|