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| Product Name | Recombinant Conus vexillum Alpha-conotoxin VxXXC |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 25.3kDa. Full Length: 1-47aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Conus vexillum (Flag cone). Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | VxXIIC |
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| Gene, Accession, CAS # | UniProt: P0C1W7 |
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| Catalog # | RPC22390 |
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| Order / More Info | Recombinant Conus vexillum Alpha-conotoxin VxXXC from BIOMATIK |
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| Product Specific References | n/a |
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