| 产品详情 |
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| Product Name | Actinomycin D |
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| Description | Purity >95%. Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low concentrations (~10 nM), which interferes with RNA synthesis and ultimately leads to cell death. Actinomycin D is widely used as an anticancer agent for treating a variety of tumors and along with its fluorescent derivative, 7-aminoactinomycin D has become a useful tool in biochemistry and molecular biology research as a marker for DNA. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-amino-N,N'-bis (hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide, Dactinomycin, Cosmegen, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K |
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| Gene, Accession, CAS # | CAS: 50-76-0 |
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| Catalog # | LS-H6398 |
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| Order / More Info | Actinomycin D from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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