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| Product Name | Human NTF4 / Neurotrophin 4 Protein (Recombinant) |
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| Description | Purity >95% by non-reducing SDS-PAGE and HPLC, MW: 14.0 kDa. Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to Beta-NGF, BDNF, and NT-3. Human NT-4 shares 48 - 52% aa sequence identity with human Beta-NGF, BDNF, and NT-3.Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. NT-4 is expressed highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 can signal through TrkB receptors and promotes the survival of peripheral sensory sympathetic neurons.Recombinant human Neurotrophin-4 (rhNT-4) produced in E.coli is a noncovalently linked homodimer containing two non-glycosylated polypeptide chains of 131 amino acids. A fully biologically active molecule, rhNT-4 has a molecular mass of 28.1kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NTF4, GLC1O, GLC10, Neurotrophic factor 5, NT-4, Neurotrophic factor 4, Neurotrophin-4, Neurotrophin-4 precursor, NT-5, NT4, NT5, NTF5, Neurotrophin 4, Neurotrophin-5, Neutrophic factor 4, NT-4/5 |
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| Gene, Accession, CAS # | NTF4, Gene ID: 4909 |
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| Catalog # | LS-G27083 |
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| Order / More Info | Human NTF4 / Neurotrophin 4 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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