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Product Name | 5-Fluorocytosine |
Description | Purity >99% by TLC. Fluorinated pyrimidine analog. Antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil (a widely used cytotoxic drug) and further metabolized to fluorinated ribo- and deoxyribonucleotides. Inhibits DNA and RNA synthesis and interfers with ribosomal protein synthesis. Displays antifungal and antitumor activity. Lately with the development of gene therapy, it has been introduced as a prodrug in combination with the cytosine deaminase suicide gene as antitumor compound, significantly improving survival and reducing tumor size in selected tumors. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 4-Amino-5-fluoro-2(1H)-pyrimidinone, 5-FC, Ancobon, Ancotil, Flucytosine, NSC 103805, Ro 2-9915 |
Gene, Accession, CAS # | CAS: 2022-85-7 |
Catalog # | LS-H1160 |
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Order / More Info | 5-Fluorocytosine from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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