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Antigenic Specificity | Suppressor of Cytokine Signaling 3 (SOCS3) |
Clone | SO1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | supernatant |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation. |
Immunogen | Full-length SOCS3 protein. |
Other Names | socs3|fj09e12|zgc:56537|wu:fj09e12|MGC64393|MGC75749|xsocs3|MGC81248|atod4|cis3|cish3|socs-3|ssi-3|ssi3|SOCS3|ATOD4|CIS3|Cish3|SOCS-3|SSI-3|SSI3|Cis3|EF-10|Ef10|Ssi3|Socs-3|Ssi-3 |
Gene, Accession # | Gene ID: 9021 |
Catalog # | ABIN94467 |
Price | |
Order / More Info | Suppressor of Cytokine Signaling 3 (SOCS3) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18045952, 18055217, 18332480, 12783879 |