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| Product Name | K252c |
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| Description | Purity >98%. K252c is a cell-permeable PKC inhibitor (IC50 s = 2.45 and 25.7 µM for PKC and PKA, respectively). It induces apoptosis in human chronic myelogenous leukemia cancer cells. In human foreskin fibroblast cells, it reduces focus formation induced by human cytomegalovirus (HCMV) strains sensitive and resistant to Ganciclovir with IC50 s of 0.32 and 0.17 µM for HCMV A6245 and HCMV-6, respectively. It also inhibits the non-kinase enzymes Beta-lactamase, chymotrypsin, and malate dehydrogenase with IC50 s of 8, 10, and 8 µM, suggesting less kinase-selectivity than was originally described. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, Staurosporine aglycone, SD 1825 |
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| Gene, Accession, CAS # | CAS: 85753-43-1 |
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| Catalog # | LS-H8319 |
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| Price | |
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| Order / More Info | K252c from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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