| 产品详情 |
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| Product Name | KC01 |
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| Description | Purity >98%. ABHD16A (also known as HLA-B associated transcript 5 (BAT5)) is a phosphatidylserine hydrolase that regulates the formation of lysophosphatidylserines (lyso-PSs) and has been implicated in certain immunological and neurological diseases. KC01 is a covalent inhibitor of ABHD16A (IC50 s = 90 and 520 nM for human and mouse, respectively). It has been shown to deplete lyso-PS from various human cancer cell lines, a lymphoblast cell line, and mouse brain membrane lysates and to decrease LPS-induced cytokine production in macrophages. This compound has been used to characterize the role of ABHD16A as a principle phosphatidylserine lipase in vivo . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6Z-(2-oxo-4-tridecyl-3-oxetanylidene), hexanamide |
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| Gene, Accession, CAS # | CAS: 1646795-59-6 |
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| Catalog # | LS-H8331 |
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| Price | |
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| Order / More Info | KC01 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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