| 产品详情 |
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| Antigenic Specificity | CD8 |
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| Clone | 53-6.7 |
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| Host Species | Rat |
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| Reactive Species | mouse, rat |
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| Isotype | IgG2a kappa |
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| Format | Protein A/G purified |
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| Size | 0.1 mg |
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| Concentration | 1 mg/ml |
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| Applications | Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Cell depletion, Inhibition of T Cell Function, CyTOF-ready. Each lot of this CD8a antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is <0.25 ug/10^6 cells in 100 uL volume. It is recommended that the reagent be titrated for optimal performance for each application. The 53-6.7 antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a+ cells. Additional reported applications (for the relevant formats) include: immunoprecipitation, in vivo and in vitro cell depletion, inhibition of CD8 T cell proliferation, blocking of cytotoxicity, and immunohistochemical staining of both acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections. Use in ICC/IF was reported in scientific literature. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24565643). |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The CD8 Antibody (53-6.7) from Novus Biologicals is a rat monoclonal antibody to CD8. This antibody reacts with mouse, rat. The CD8 Antibody (53-6.7) has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Cell depletion, Inhibition of T Cell Function, CyTOF-ready. |
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| Immunogen | Mouse thymus or spleen. |
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| Other Names | 53-6.7, 53-6.7 CD8, 53-6.7 CD8 Alpha, 53-6.7 CD8 Aplha, 53-6.7 Clone, CD8, CD8a molecule, Cytotoxic T cell marker, Cytotoxic T lymphocyte marker, LEU2, p32, T cell marker |
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| Gene, Accession # | CD8A, Gene ID: 925 |
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| Catalog # | NBP1-49045SS |
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| Price | |
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| Order / More Info | CD8 Antibody from NOVUS BIOLOGICALS, LLC |
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| Product Specific References | PubMed: 11877283, 1608966, 20211938, 21458857, 24565643, 27831762, 28368410, 28592285, 28904063, 29367423, 30549327, 398327 |
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