| 产品详情 |
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| Product Name | SAMS Peptide |
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| Description | AMP-activated protein kinase (AMPK) plays a role in energy metabolism and glucose homeostasis by monitoring the ratio of ATP to AMP. This kinase can inactivate HMG-CoA reductase and acetyl-CoA carboxylase as well as block the activation of hormone-sensitive lipase by cyclic-AMP-dependent protein kinase (protein kinase A or PKA). SAMS peptide is a synthetic peptide substrate for AMPK based on the sequence around Ser79 (which is phosphorylated exclusively by AMPK) on acetyl-CoA carboxylase. In this sequence, Ser77 (which is phosphorylated exclusively by PKA) is replaced by alanine to eliminate a neighboring binding site for PKA. This substitution yields a substrate more specific for AMPK than acetyl-CoA carboxylase itself. SAMS peptide is phosphorylated rapidly by AMPK, providing a convenient and sensitive tool for assaying AMPK activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 125911-68-4 |
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| Catalog # | LS-H5428 |
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| Order / More Info | SAMS Peptide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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