| 产品详情 |
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| Product Name | KN-62 |
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| Description | Purity >98%. Cell-permeable. KN-62 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII; IC50= 900 nM). It binds directly to the calmodulin binding site of the enzyme. It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester |
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| Gene, Accession, CAS # | CAS: 127191-97-3 |
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| Catalog # | LS-H3069 |
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| Price | |
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| Order / More Info | KN-62 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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