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| Product Name | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) protein (Fc Tag) |
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| Description | Cytotoxic T-lymphocyte protein 4, is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4. Synonyms: Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,CTLA4,CD152 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CTLA-4|CTLA4|CD152|Cd152|Ctla-4|Ly-56|CD|CELIAC3|GRD4|GSE|IDDM12|sCTLA4 |
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| Gene, Accession, CAS # | Gene ID: 1493 |
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| Catalog # | ABIN2115353 |
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| Order / More Info | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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