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Antigenic Specificity | Phospho-Syntaxin 1 (Ser14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-Syntaxin 1 (Ser14) Polyclonal Antibody. Syntaxin 1 is a small integral membrane protein that is abundantly expressed in neurons and neuroendocrine cells and thought to be implicated in the regulation of synaptic neurotransmitter release. Syntaxin 1 interacts with several other proteins important for synaptic function (SNAP 25, Munc 18). Syntaxin 1 is the main target of one of the Botulinum neurotoxins (BoNT/C1) which, however, cannot cleave the protein when complexed with its partner proteins in the fusion complex. Syntaxin 1 is an essential component of the neurotransmitter release machinery, and regulation of Syntaxin 1 expression levels is thought to contribute to the mechanism underlying learning and memory. |
Immunogen | n/a |
Other Names | Neuron-specific antigen HPC-1, P35A, SAP, STX1, Synaptotagmin associated 35 kDa protein, syntaxin 1A |
Gene, Accession # | Entrez: 116470, 20907, 6804; Uniprot: O35526, P32851, Q16623 |
Catalog # | PA5-38923 |
Price | |
Order / More Info | Phospho-Syntaxin 1 (Ser14) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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