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| Product Name | 2-hexyl-4-Pentynoic Acid |
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| Description | Purity >95%. 2-hexyl-4-Pentynoic acid is a derivative of valproic acid , an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM). 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM. It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(2-propyn-1-yl)-octanoic acid |
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| Gene, Accession, CAS # | CAS: 96017-59-3 |
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| Catalog # | LS-H5990 |
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| Order / More Info | 2-hexyl-4-Pentynoic Acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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