产品详情 |
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Antigenic Specificity | Orexin A (aa 14-33) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Bovine Orexin A (aa 14-33) polyclonal antibody for IHC. Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy. |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 3060, UniProt: O43612 |
Catalog # | DPAB3845 |
Price | |
Order / More Info | Orexin A (aa 14-33) Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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