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| Product Name | Recombinant Human Bile acid receptor (NR1H4) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 70.7kDa. Full Length of Isoform 3: 1-476aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Farnesoid X-activated receptorFarnesol receptor HRR-1Nuclear receptor subfamily 1 group H member 4Retinoid X receptor-interacting protein 14; RXR-interacting protein 14 |
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| Gene, Accession, CAS # | NR1H4, UniProt: Q96RI1 |
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| Catalog # | RPC23382 |
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| Order / More Info | Recombinant Human Bile acid receptor (NR1H4) from BIOMATIK |
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| Product Specific References | n/a |
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