| 产品详情 |
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| Product Name | PR-619 |
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| Description | Purity >98%. PR-619 is a general inhibitor of deubiquitylating enzymes (DUBs), significantly reducing the activity of a panel of DUBs with EC50 values ranging from 5-20 µM. It is cell-permeable and reversible in its action. It is selective for DUBs over other proteases. PR-619 induces the accumulation of polyubiquitinated proteins in cells, including those not involved in the ubiquitin-proteasome system. It is used to study the role of DUBs in diverse pathways, including protein turnover and neurodegeneration. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C,C'-(2,6-diamino-3,5-pyridinediyl) ester thiocyanic acid, 2,6-Diamino-3,5-dithiocyanopyridine, DUB Inhibitor V |
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| Gene, Accession, CAS # | CAS: 2645-32-1 |
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| Catalog # | LS-H9491 |
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| Order / More Info | PR-619 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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