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| Product Name | CGP 35348 |
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| Description | Purity >95%. The amino acid Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC, and a G protein-coupled receptor, GABAB . CGP 35348 is a selective, brain-accessible GABAB receptor antagonist (IC50 = 34 µM). It blocks the action of the GABAB -selective agonist baclofen at postsynaptic sites but not at presynaptic receptors. CGP 35348 prevents baclofen-induced antinociception and muscle relaxation in mice and rats. It is commonly used to investigate the role of GABAB activation in neurological signaling. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | P-(3-aminopropyl)-P-(diethoxymethyl)-phosphinic acid |
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| Gene, Accession, CAS # | CAS: 123690-79-9 |
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| Catalog # | LS-H7093 |
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| Order / More Info | CGP 35348 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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