| 产品详情 |
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| Product Name | CGP 37157 |
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| Description | Purity >99%. CGP 37157 is a benzothiazepine that acts as a selective inhibitor of the mitochondrial sodium-calcium exchanger (IC50 = 0.36 µM in isolated mitochondria). It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 is commonly used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. CGP 37157 inhibits sodium-dependent calcium efflux via the mitochondrial exchanger NCLX in a variety of cell types (IC50 = 5 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one |
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| Gene, Accession, CAS # | CAS: 75450-34-9 |
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| Catalog # | LS-H7094 |
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| Order / More Info | CGP 37157 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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