产品详情 |
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Antigenic Specificity | Human CD99 |
Clone | KG1002 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, ICC/IF, IHC, IP, FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human CD99 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. MIC2, also designated CD99, is a T cell surface protein that is involved in the aggregation of lymphocytes. Two forms of MIC2, which are differentially expressed, are produced by alternative splicing. The major form induces cellular adhesion, whereas the truncated form inhibits the adhesion process. MIC2 regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes. Overexpression of the truncated form results in downregulated expression of LFA-1. Cells with downregulated MIC2 exhibit a Hodgkin's and Reed-Sternberg (H-RS) phenotype, indicating that MIC2 plays an important role in regulating cell function and morphology. |
Immunogen | Recombinant Protein |
Other Names | n/a |
Gene, Accession # | Gene ID: 4267, UniProt: P14209 |
Catalog # | CABT-L872 |
Price | |
Order / More Info | Human CD99 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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