产品详情 |
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Antigenic Specificity | Human CDC42EP1 |
Clone | TE19-65 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human CDC42EP1 monoclonal antibody for WB. MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling. |
Immunogen | Recombinant Protein |
Other Names | n/a |
Gene, Accession # | Gene ID: 11135, UniProt: Q00587 |
Catalog # | DCABH-4269 |
Price | |
Order / More Info | Human CDC42EP1 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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