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| Antigenic Specificity | Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (aa 470-503) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.Subunit: Homotetramer or heterotetramer with other ASIC proteins (Probable). Interacts with STOM. Interacts with PRKCABP and ACCN3.Subcellular location: Cell membrane, Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. Also known as: Amiloride-sensitive brain sodium channel, acid-sensing ion channel 2, ASIC2, brain sodium channel 1, BNaC1, BNC1, mammalian degenerin homolog, ACCN, BNAC1, MDEG. |
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| Immunogen | A synthetic peptide from aa region 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
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| Other Names | ACCN|ACCN1|ASIC2a|BNC1|BNaC1|MDEG|hBNaC1|ACIC2|Accn1|BNaC1a|Mdeg|BNC1k|MDEG1|MDEG2|accn1|zASIC2|BNC|BSN1|HsT19447|AI047752|AW546376|Bnc |
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| Gene, Accession # | Gene ID: 40,11418,25364 |
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| Catalog # | ABIN350041 |
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| Order / More Info | Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (aa 470-503) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 10842183, 9037075, 11802773, 8626462, 8631835 |
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