| 产品详情 |
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| Product Name | TBCA |
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| Description | Purity >98%. Casein kinase 2 (CK2) is a kinase with many targets and diverse roles in cell signaling and disease. TBCA is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 µM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 µM), driving caspase-dependent degradation of poly-ADP ribose polymerase while inhibiting CK2 activity. TBCA also supports a role for CK2 in platelet function and Akt phosphorylation but not protein splicing. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2E)-3-(2,3,4,5-tetrabromophenyl)-2-propenoic acid, Casein Kinase II Inhibitor III, Tetrabromocinnamic Acid |
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| Gene, Accession, CAS # | CAS: 934358-00-6 |
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| Catalog # | LS-H10117 |
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| Price | |
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| Order / More Info | TBCA from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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