产品详情 |
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Antigenic Specificity | Lass5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 20 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lass5 Polyclonal Antibody. The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-cera |
Immunogen | n/a |
Other Names | LASS5, Trh4; LAG1 homolog, ceramide synthase 5; LAG1 longevity assurance homolog 5 |
Gene, Accession # | Entrez: 366984, 71949, 91012; Uniprot: Q8N5B7, Q9D6K9 |
Catalog # | PA5-20569 |
Price | |
Order / More Info | Lass5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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